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Protocol Resources for Red Blood Cell Removal

Cell Separation Methods

Red Blood Cell Removal

When isolating specific cell types from blood for functional studies or downstream assays, red blood cell (RBC) depletion may be required. Here are technical tips and protocols on how to deplete RBCs from blood samples prior to cell separation, including how to remove RBCs from different types of blood samples and how to deplete RBCs without ammonium chloride lysis.

Learn about cell isolation from blood >


Technical Bulletin Depletion of Red Blood Cells from Fresh Blood Samples
Video How to Isolate Nucleated Cells from Whole Blood Using HetaSep™ Erythrocyte Aggregation Agent
Video How to Deplete Red Blood Cells from Small Volume Samples with HetaSep™
Protocol How to Prepare a Polymorphonuclear Cell Fraction from Whole Blood Using Ammonium Chloride Lysis
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