Cell Therapy Research
Cell therapy research involves investigating novel ways to use cells to treat diseases or disorders. Cell-based therapies resulting from this research have the potential to treat a range of systemic diseases by acting as "living drugs".
A variety of cell types may be used as cell therapies, including hematopoietic stem cells, pluripotent stem cells, immune cells, and more. These cells may be purified (e.g. bone marrow transplants), expanded, or further manipulated through genome editing (e.g. CAR T cells).
What is cell therapy?
Cell therapy is a therapeutic intervention involving the transfer of live cells into patients. As cell therapy research and clinical trials progress, the number of clinical applications for cell therapy continues to increase. Cell therapy can potentially be used for the treatment of hematological malignancies, solid tumors, non-malignant hematological disorders, and autoimmune diseases, among other conditions.
What types of cells can be used for cell therapy?
A variety of cell types may be used as cell therapies, including hematopoietic stem cells, pluripotent stem cells, and immune cells (e.g. T cells, NK cells). Prior to use, these cells may be purified, expanded, or further manipulated through genome editing. For example, T cells can be engineered to express chimeric antigen receptors (CARs), which are synthetic transmembrane receptors that help redirect T cell specificity (e.g. toward cancer cells).
What are some challenges in the field of cell therapy?
There are many steps involved in producing cell therapies, each with its own challenges. Researchers need to obtain an adequate number of cells with the desired phenotypes, effectively perform genetic modifications, and evaluate the potency of the cell therapy. Manufacturers also face many challenges, including navigating the regulatory landscape and solving complex manufacturing and product delivery logistics.
What tools and technologies are used in cell therapy research?
A wide variety of tools and technologies are required to perform cell therapy research, including tools for cell isolation, activation, expansion, differentiation, and characterization. STEMCELL can support your immune cell, hematopoietic cell, and stem cell therapy research with our specialized cell culture media and cell isolation products. For personalized support and tailored solutions, we offer a Services for Cell Therapy Program that can also help you navigate the cell therapy manufacturing landscape.
Resources for Cell Therapy Research
With new publications, clinical trials, techniques, and technologies, cell therapy research is evolving quickly. To help you explore this exciting and complex field, we have collected a series of scientific resources in the research areas below:
- Resource Type
-
- Interview 3 items
- Podcast 8 items
- Protocol 1 item
- Scientific Poster 7 items
- Tech Tip 7 items
- Technical Bulletin 3 items
- Video 5 items
- Wallchart 2 items
- Webinar 29 items
- White Paper 1 item
- Product Type
-
- Cell Culture Media and Supplements 34 items
- Cell Dyes and Detection Assay Kits 3 items
- Cell Engineering and Molecular Tools 3 items
- Cell Isolation Products 3 items
- Primary and Cultured Cells 2 items
- Area of Interest
-
- Cancer 7 items
- Cell Line Development 3 items
- Cell Therapy Research 34 items
- Cord Blood Banking 4 items
- Disease Modeling 10 items
- Drug Discovery and Toxicity Testing 12 items
- Immunology 8 items
- Neuroscience 3 items
- Organoids 4 items
- Stem Cell Biology 34 items
- Transplantation Research 5 items
- Brand
-
- ALDECOUNT 2 items
- ALDEFLUOR 2 items
- ArciTect 7 items
- CellAdhere 1 item
- CryoStor 1 item
- ES-Cult 4 items
- EasySep 7 items
- ImmunoCult 7 items
- MammoCult 1 item
- MesenCult 1 item
- MethoCult 7 items
- MyoCult 1 item
- NeuroCult 1 item
- PBS-MINI 2 items
- ProstaCult 1 item
- STEMdiff 13 items
- STEMgrid 2 items
- STEMvision 2 items
- SmartDish 1 item
- StemSpan 16 items
- TeSR 18 items
- mFreSR 4 items
- Category
- Cell Type
-
- Airway Cells 1 item
- B Cells 3 items
- Cardiomyocytes, PSC-Derived 5 items
- Dendritic Cells 2 items
- Endoderm, PSC-Derived 5 items
- Endothelial Cells, PSC-Derived 4 items
- Epithelial Cells, PSC-Derived 5 items
- Erythroid Cells 3 items
- Hematopoietic Cells, PSC-Derived 8 items
- Hematopoietic Stem and Progenitor Cells 19 items
- Hepatic Cells, PSC-Derived 4 items
- Innate Lymphoid Cells 1 item
- Intestinal Cells 1 item
- Leukocytes 1 item
- Leukopaks 1 item
- Lymphocytes 5 items
- Macrophages 2 items
- Mammary Cells 2 items
- Megakaryocytes 1 item
- Mesenchymal Cells, PSC-Derived 5 items
- Mesenchymal Stem and Progenitor Cells 2 items
- Mesenchymal Stromal Cells 1 item
- Mesoderm, PSC-Derived 4 items
- Microglia 1 item
- Monocytes 3 items
- Mononuclear Cells 1 item
- Myeloid Cells 2 items
- Myogenic Stem and Progenitor Cells 1 item
- NK Cells 4 items
- Neural Cells, PSC-Derived 5 items
- Neural Stem and Progenitor Cells 1 item
- Pancreatic Cells 1 item
- Platelets 1 item
- Pluripotent Stem Cells 24 items
- Prostate Cells 1 item
- Red Blood Cells 1 item
- T Cells 18 items
- T Cells, CD4+ 6 items
- T Cells, CD8+ 5 items
- T Cells, Other Subsets 1 item
- T Cells, Regulatory 5 items
- Whole 1 item